Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP4 | P49662 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148890 | 0.90 | MEN1 (0.38) | KMT2AMEN1RAB9ANR1H4CASP6 | |
| SCHEMBL9144351 | 0.90 | CASP6 (0.39) | KMT2AMEN1RAB9ANR1H4CASP6 | |
| SCHEMBL9144401 | 0.89 | KMT2A (0.40) | KMT2AMEN1RAB9ANR1H4CASP6 | |
| SCHEMBL9148298 | 0.89 | HTT (0.38) | KMT2AMEN1RAB9ANR1H4CASP6 | |
| SCHEMBL9150069 | 0.88 | KMT2A (0.38) | KMT2AMEN1RAB9ANR1H4CASP6 | |
| SCHEMBL9147836 | 0.88 | MEN1 (0.39) | KMT2AMEN1RAB9ANR1H4CASP6 | |
| SCHEMBL9148151 | 0.88 | KMT2A (0.36) | KMT2AMEN1RAB9ANR1H4CASP6 | |
| SCHEMBL9150684 | 0.88 | KMT2A (0.38) | KMT2AMEN1RAB9ANR1H4CASP6 | |
| SCHEMBL9146730 | 0.87 | MEN1 (0.35) | KMT2AMEN1RAB9ANR1H4CASP6 | |
| SCHEMBL9144578 | 0.87 | KMT2A (0.40) | KMT2AMEN1RAB9ANR1H4CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143924-A | OXODIHYDROPYRIDYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |