Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PGD | P52209 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20839610 | 0.97 | TSHR (0.50) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL11797114 | 0.86 | TSHR (0.45) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1707892 | 0.80 | TDP1 (0.50) | TSHRPGDLMNA | |
| SCHEMBL11767716 | 0.80 | SLC1A3 (0.41) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1068276 | 0.79 | TSHR (0.50) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7591556 | 0.78 | TSHR (0.43) | TSHRSLC1A3SLC1A2SLC1A1CYP2C9 | |
| SCHEMBL3680538 | 0.77 | TSHR (0.47) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7291825 | 0.77 | SLC1A3 (0.54) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7290471 | 0.77 | SLC1A3 (0.54) | TSHRTP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7516079 | 0.77 | TSHR (0.47) | TSHRTP53SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935493-A1 | CURABLE SILSESQUIOXANE POLYMERS, COMPOSITIONS, ARTICLES, AND METHODS | 3M Innovative Properties Company (US) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014099699-A1 | CURABLE SILSESQUIOXANE POLYMERS, COMPOSITIONS, ARTICLES, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-06-26 | — | — | WO | disclosed |
| US-8597419-B2 | Preservative compositions for wood and like materials | GENICS INC. (CA) | 2013-12-03 | — | — | US | disclosed |
| US-20110275708-A1 | POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO | CORNELL UNIVERSITY (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110135829-A1 | ESTER-BASED CONCRETE SURFACE RETARDERS | VERIFI LLC | 2011-06-09 | — | — | US | disclosed |
| US-20110021854-A1 | METHOD OF CONVERTING ETHYLBENZENE AND PROCESS FOR PRODUCING P-XYLENE | TORAY INDUSTRIES, INC. (JP) | 2011-01-27 | — | — | US | disclosed |
| US-20100062166-A1 | PRESERVATIVE COMPOSITIONS FOR WOOD AND LIKE MATERIALS | GENICS INC. (CA) | 2010-03-11 | — | — | US | disclosed |
| CN-1531584-A | Fuel oil additive and fuel oil product containing same | 呼世滨 | 2004-09-22 | — | — | CN | disclosed |
| US-5028415-A | Poly/epoxysuccinic Acid/ | THE PROCTER & GAMBLE COMPANY (US) | 1991-07-02 | — | — | US | disclosed |
| US-4846650-A | SUCCINIC ACID OR SALT DERIVATIVE AS ADDUCT OR POLYETHER | THE PROCTER & GAMBLE COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| US-4798675-A | Corrosion inhibiting compositions containing carboxylated phosphonic acids and sequestrants | THE MOGUL CORPORATION (US) | 1989-01-17 | — | — | US | disclosed |
| US-4654159-A | SEQUESTERING, LAUNDERING, EPOXYSUCCINATE, CALCIUM COMPOUND | THE PROCTER & GAMBLE COMPANY (US) | 1987-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275708-A1 | POLYCYCLIC COMPOUNDS AND METHODS RELATED THERETO | PKD1, THPO, CCNO | TSHR 4788/4885TP53 60/4885SLC1A3 1765/4885 |
| US-20110021854-A1 | METHOD OF CONVERTING ETHYLBENZENE AND PROCESS FOR PRODUCING P-XYLENE | MLLT1, SMARCC2, SMARCC1 | TSHR 4641/4885TP53 1215/4885SLC1A3 4793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.