SCHEMBL1707892

SCHEMBL1707892

O=C(O)CC(C(=O)O)C(OC(C(=O)O)C(O)C(=O)O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.38
SLC22A6 Q4U2R8 1/20 0.36
TSHR P16473 1/20 0.35
PGD P52209 3/20 0.33
GABRR1 P24046 2/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL915072 0.80 TSHR (0.53) TSHRPGDLMNA
SCHEMBL20839610 0.78 TSHR (0.50) TSHRPGD
SCHEMBL9573234 0.78 TDP1 (0.52) TDP1SMN1; SMN2SLC22A6
SCHEMBL8430241 0.78 SMN1; SMN2 (0.39) TDP1SMN1; SMN2SLC22A6TSHRPGD
SCHEMBL1707888 0.77 TDP1 (0.46) TDP1SMN1; SMN2SLC22A6TSHRPGD
SCHEMBL1289946 0.76 TDP1 (0.45) TDP1SMN1; SMN2SLC22A6TSHRPGD
Isocitrate SCHEMBL1289944 0.75 TDP1 (0.68) TDP1SMN1; SMN2SLC22A6TSHRGABRR1
Isocitric Acid SCHEMBL12927570 0.75 TDP1 (0.68) TDP1SMN1; SMN2SLC22A6TSHRGABRR1
Isocitric Acid SCHEMBL6249818 0.75 TDP1 (0.68) TDP1SMN1; SMN2SLC22A6TSHRGABRR1
Isocitrate SCHEMBL8373 0.75 TDP1 (0.68) TDP1SMN1; SMN2SLC22A6TSHRGABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1755003-B1 Stripper ROHM & HAAS ELECT MAT (US) 2012-04-18 EP claimed
US-7723280-B2 Stripper for electronics ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2010-05-25 US claimed
US-20070066502-A1 comprising 0.05 to 5% wt of a fluoride source, 40 to 95% wt of a solvent mixture comprising a polyhydric alcohol and an ether, 5 to 50% wt water, and a pH adjuster chosen from carbonic acid or its salt and a polycarboxylic acid and a base, where the molar ratio of polycarboxylic acid to the base is 1:1 ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2007-03-22 US claimed
EP-1755003-A1 Stripper Rohm and Haas Electronic Materials LLC (US) 2007-02-21 EP claimed