SCHEMBL9150780

SCHEMBL9150780

CCN(CC)c1ccc(C=O)cc1.NN(c1ccccc1)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.70
ALDH3A1 P30838 1/20 0.70
ALDH1A3 P47895 1/20 0.70
ESRRG P62508 1/20 0.46
KMT2A Q03164 5/20 0.45
MEN1 O00255 4/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
NOX1 Q9Y5S8 1/20 0.45
MAPT P10636 7/20 0.45
KDM4E B2RXH2 5/20 0.45
GAA P10253 4/20 0.45
TDP1 Q9NUW8 3/20 0.45
LMNA P02545 3/20 0.45
MAPK1 P28482 2/20 0.45
HPGD P15428 2/20 0.45
POLB P06746 2/20 0.45
CNR2 P34972 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MITF O75030 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11220728 0.88 ALDH1A1 (0.78) ALDH1A1ALDH3A1ALDH1A3ESRRGKMT2A
SCHEMBL15557461 0.88 ALDH1A1 (0.54) ALDH1A1ALDH3A1ALDH1A3KMT2AMEN1
Biphenyl SCHEMBL1200005 0.84 ALDH1A1 (0.78) ALDH1A1ALDH3A1ALDH1A3ESRRGKMT2A
SCHEMBL5733313 0.84 ALDH1A1 (1.00) ALDH1A1ALDH3A1ALDH1A3KMT2AMEN1
SCHEMBL195135 0.84 ALDH1A1 (1.00) ALDH1A1ALDH3A1ALDH1A3KMT2AMEN1
SCHEMBL11196847 0.82 ALDH1A1 (0.81) ALDH1A1ALDH3A1ALDH1A3ESRRGKMT2A
SCHEMBL2819330 0.82 CYP2A6 (0.52) ALDH1A1ALDH3A1ALDH1A3KMT2AMEN1
Hydrochloric Acid SCHEMBL11145003 0.82 ALDH1A1 (0.95) ALDH1A1ALDH3A1ALDH1A3KMT2AMEN1
Phenylhydrazine SCHEMBL27601695 0.81 ALDH1A1 (0.66) ALDH1A1ALDH3A1ALDH1A3ESRRGKMT2A
Hydrazobenzene SCHEMBL27601693 0.80 ALDH1A1 (0.70) ALDH1A1ALDH3A1ALDH1A3ESRRGKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4471040-A Electrophotographic disazo photosensitive member CANON KABUSHIKI KAISHA (JP) 1984-09-11 US claimed
EP-0371791-B1 Electrophotographic photosensitive material MITA INDUSTRIAL CO LTD (JP) 1995-01-25 EP disclosed
US-5168024-A Matrix for charge transfer compound FUJI XEROX CORPORATION, LTD. (JP) 1992-12-01 US disclosed
US-5024913-A Surface protective coating containing silicone resin and 1,8-diazabicyclo(5.4.0)undec-7-ene curing agent MITA INDUSTRIAL CO., LTD. (JP) 1991-06-18 US disclosed
EP-0371791-A2 Electrophotographic photosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1990-06-06 EP disclosed
EP-0153145-B1 PHOTORECEPTOR KONICA CORPORATION (JP) 1988-06-08 EP disclosed