Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049759 | 1.00 | TSHR (0.59) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL21061174 | 1.00 | TSHR (0.59) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16516272 | 1.00 | TSHR (0.59) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7083571 | 0.98 | TSHR (0.61) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL30807225 | 0.93 | TSHR (0.62) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16135260 | 0.89 | ALDH1A1 (0.54) | TSHRALDH1A1HSD17B10FFAR1 | |
| SCHEMBL3731031 | 0.87 | TSHR (0.49) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3732352 | 0.87 | TSHR (0.49) | TSHRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3170534 | 0.85 | TSHR (0.67) | TSHRMEN1KMT2AMAPTRAB9A | |
| SCHEMBL9383990 | 0.82 | TSHR (0.54) | TSHRMEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35096-E | Antilipemic, anticholesterol, arteriosclerosis | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-11-21 | — | — | US | disclosed |
| US-5082856-A | Hyperlipemia, arteriosclerosis | MITSUBISHI KASEI CORPORATION (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0347902-A2 | Pyrrolecarboxylic acid derivatives | Mitsubishi Chemical Corporation (JP) | 1989-12-27 | — | — | EP | disclosed |