Chloroform

Chloroform

SCHEMBL9150901

ClC(Cl)Cl.O=C(O)Cc1ccccn1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTPRA P18433 1/20 0.56
RAB9A P51151 4/20 0.56
NPC1 O15118 3/20 0.56
SMN1; SMN2 Q16637 4/20 0.50
POLB P06746 1/20 0.50
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47
FDPS P14324 1/20 0.47
PTGDR2 Q9Y5Y4 1/20 0.46
SIGMAR1 Q99720 1/20 0.46
IDO1 P14902 1/20 0.45
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
KMT2A Q03164 1/20 0.45
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloroform SCHEMBL11654992 0.96 PTPRA (0.53) PTPRARAB9ANPC1SMN1; SMN2POLB
Benzene SCHEMBL11747977 0.94 PTPRA (0.56) PTPRARAB9ANPC1SMN1; SMN2POLB
SCHEMBL29676689 0.94 PTPRA (0.56) PTPRARAB9ANPC1SMN1; SMN2POLB
SCHEMBL21298 0.94 PTPRA (0.56) PTPRARAB9ANPC1SMN1; SMN2POLB
Hydrochloric Acid SCHEMBL334937 0.92 PTPRA (0.55) PTPRARAB9ANPC1SMN1; SMN2POLB
SCHEMBL988403 0.92 PTPRA (0.55) PTPRARAB9ANPC1SMN1; SMN2POLB
Water SCHEMBL5531145 0.92 PTPRA (0.55) PTPRARAB9ANPC1SMN1; SMN2POLB
Iodide SCHEMBL2108436 0.92 PTPRA (0.55) PTPRARAB9ANPC1SMN1; SMN2POLB
Water SCHEMBL29453011 0.92 PTPRA (0.55) PTPRARAB9ANPC1SMN1; SMN2POLB
Water SCHEMBL29453010 0.92 PTPRA (0.55) PTPRARAB9ANPC1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0470086-B1 PROCESS FOR THE PURIFICATION OF HEMIN, A NOVEL HEMIN DERIVATIVE AND A PROCESS FOR ITS PREPARATION LEIRAS OY (FI) 1995-01-11 EP disclosed
US-5233034-A PROCESS FOR THE PURIFICATION OF HEMIN, A NOVEL DERIVATIVE AND PROCESS FOR ITS PREPARATION HUHTAMAKI OY (FI) 1993-08-03 US disclosed