Iodide

Iodide

SCHEMBL2108436

I.O=C(O)Cc1ccccn1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTPRA P18433 1/20 0.55
RAB9A P51151 5/20 0.54
NPC1 O15118 4/20 0.54
SMN1; SMN2 Q16637 5/20 0.53
POLB P06746 1/20 0.53
CYP1A2 P05177 3/20 0.50
CYP2C19 P33261 1/20 0.50
PTGDR2 Q9Y5Y4 1/20 0.48
IDO1 P14902 1/20 0.47
ALDH1A1 P00352 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47
GAA P10253 1/20 0.47
TSHR P16473 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL11747977 0.98 PTPRA (0.56) PTPRARAB9ANPC1SMN1; SMN2POLB
SCHEMBL29676689 0.98 PTPRA (0.56) PTPRARAB9ANPC1SMN1; SMN2POLB
SCHEMBL21298 0.98 PTPRA (0.56) PTPRARAB9ANPC1SMN1; SMN2POLB
Water SCHEMBL29453011 0.96 PTPRA (0.55) PTPRARAB9ANPC1SMN1; SMN2POLB
Hydrochloric Acid SCHEMBL6491192 0.96 PTPRA (0.55) PTPRARAB9ANPC1SMN1; SMN2POLB
Water SCHEMBL29453010 0.96 PTPRA (0.55) PTPRARAB9ANPC1SMN1; SMN2POLB
SCHEMBL988403 0.96 PTPRA (0.55) PTPRARAB9ANPC1SMN1; SMN2POLB
Water SCHEMBL5531145 0.96 PTPRA (0.55) PTPRARAB9ANPC1SMN1; SMN2POLB
Hydrochloric Acid SCHEMBL334937 0.96 PTPRA (0.55) PTPRARAB9ANPC1SMN1; SMN2POLB
SCHEMBL26119096 0.96 PTPRA (0.55) PTPRARAB9ANPC1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112384520-B Method for producing oligonucleotide compound 日本新药株式会社 2024-06-11 CN disclosed
US-20240116977-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-04-11 US disclosed
US-20240051986-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-02-15 US disclosed
WO-2023182274-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER 住友化学株式会社 2023-09-28 WO disclosed
EP-4219520-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-08-02 EP disclosed
CN-116209668-A Method for producing nucleic acid oligomer 住友化学株式会社 2023-06-02 CN disclosed
CN-116063365-A Method for preparing oligonucleotide and nucleoside, nucleotide or oligonucleotide 味之素株式会社 2023-05-05 CN disclosed
US-11560401-B2 Method for preparing oligonucleic acid compound NIPPON SHINYAKU CO., LTD. (JP) 2023-01-24 US disclosed
US-20230014840-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND NIPPON SHINYAKU CO., LTD. (JP) 2023-01-19 US disclosed
US-20230018780-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND NIPPON SHINYAKU CO., LTD. (JP) 2023-01-19 US disclosed
US-20120296074-A1 PRODUCTION METHOD OF OLIGONUCLEOTIDE AJINOMOTO CO., INC. (JP) 2012-11-22 US disclosed
EP-1795536-B1 PHOSPHORAMIDITE COMPOUND AND METHOD FOR PRODUCING OLIGO-RNA NIPPON SHINYAKU CO LTD (JP) 2012-05-02 EP disclosed
US-8158774-B2 Method for introducing a nucleic-acid protecting group NIPPON SHINYAKU CO., LTD. (JP) 2012-04-17 US disclosed
US-8158775-B2 Method for detaching protecting group on nucleic acid NIPPON SHINYAKU CO., LTD. (JP) 2012-04-17 US disclosed
US-20090312534-A1 METHOD FOR REMOVAL OF NUCLEIC ACID-PROTECTING GROUP NIPPON SHINYAKU CO., LTD. (JP) 2009-12-17 US disclosed
US-20090286970-A1 METHOD FOR INTRODUCING A NUCLEIC-ACID PROTECTING GROUP NIPPON SHINYAKU CO., LTD. (JP) 2009-11-19 US disclosed
US-20090149645-A1 METHOD FOR DETACHING PROTECTING GROUP ON NUCLEIC ACID NIPPON SHINYAKU CO., LTD. (JP) 2009-06-11 US disclosed
US-20090137790-A1 METHOD OF CAPPING OLIGONUCLEIC ACID NIPPON SHINYAKU CO., LTD. (JP) 2009-05-28 US disclosed
US-20070282097-A1 Phosphoramidite Compound And Method For Producing Oligo-Rna NIPPON SHINYAKU CO., LTD. (JP) 2007-12-06 US disclosed
EP-1795536-A1 PHOSPHORAMIDITE COMPOUND AND METHOD FOR PRODUCING OLIGO-RNA Nippon Shinyaku Co., Ltd. (JP) 2007-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240051986-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMER POLRMT, NOP2, POLN PTPRA 3995/4885RAB9A 4718/4885NPC1 614/4885
US-20090312534-A1 METHOD FOR REMOVAL OF NUCLEIC ACID-PROTECTING GROUP NSUN2, RNASEH1, RNASE1 PTPRA 4074/4885RAB9A 3857/4885NPC1 2202/4885
US-20090137790-A1 METHOD OF CAPPING OLIGONUCLEIC ACID RNGTT, DUT, ADAR PTPRA 1236/4885RAB9A 4438/4885NPC1 4022/4885
US-20230018780-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND POLRMT, POLR2H, POLM PTPRA 3123/4885RAB9A 4007/4885NPC1 4345/4885
US-20070282097-A1 Phosphoramidite Compound And Method For Producing Oligo-Rna NSUN2, NSUN3, XRN2 PTPRA 3987/4885RAB9A 3968/4885NPC1 4668/4885
US-20090286970-A1 METHOD FOR INTRODUCING A NUCLEIC-ACID PROTECTING GROUP RNASEH1, SNRPB2, SNRPA1 PTPRA 4632/4885RAB9A 4556/4885NPC1 2366/4885
US-11560401-B2 Method for preparing oligonucleic acid compound POLRMT, POLI, POLR2H PTPRA 3273/4885RAB9A 3816/4885NPC1 2349/4885
US-20090149645-A1 METHOD FOR DETACHING PROTECTING GROUP ON NUCLEIC ACID DNASE1, DNASE1L3, NSUN2 PTPRA 3738/4885RAB9A 4480/4885NPC1 2295/4885
US-20120296074-A1 PRODUCTION METHOD OF OLIGONUCLEOTIDE RNGTT, POLM, RNMT PTPRA 842/4885RAB9A 4874/4885NPC1 3785/4885
US-20230014840-A1 METHOD FOR PRODUCING OLIGONUCLEIC ACID COMPOUND DNASE1, XRN2, FBL PTPRA 4646/4885RAB9A 4449/4885NPC1 1308/4885
US-20240116977-A1 METHOD FOR PRODUCING NUCLEIC ACID OLIGOMERS NOP2, DIS3, POLRMT PTPRA 4678/4885RAB9A 4453/4885NPC1 1177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.