SCHEMBL9151111

SCHEMBL9151111

CCCCCCCCOc1ccc(-c2cc(CCc3ccc(CCCC[Si](C)(C)CCC[Si](C)(C)C)cc3)ccc2C(=O)O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 4/20 0.51
RARB P10826 9/20 0.47
RARA P10276 2/20 0.47
RARG P13631 1/20 0.47
PTPRC P08575 1/20 0.45
PTPRF P10586 1/20 0.45
PTPN1 P18031 1/20 0.45
CDC25A P30304 1/20 0.45
CDC25B P30305 1/20 0.45
CDC25C P30307 1/20 0.45
PPP1CC P36873 1/20 0.45
PPARA Q07869 2/20 0.45
PPARG P37231 1/20 0.45
MEN1 O00255 1/20 0.43
USP2 O75604 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPK1 P28482 1/20 0.43
CASP1 P29466 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9148524 0.94 PTPN11 (0.48) PTPN11RARBRARARARGPTPRC
SCHEMBL9151096 0.89 PTPN11 (0.46) PTPN11RARBRARARARGPTPRC
SCHEMBL8912209 0.88 PTPN11 (0.56) PTPN11RARBRARARARGMEN1
SCHEMBL9148117 0.88 PTPN11 (0.46) PTPN11RARBRARARARGPTPRC
SCHEMBL11138404 0.87 PTPN11 (0.61) PTPN11RARBRARARARGPPARA
SCHEMBL11133724 0.87 PTPN11 (0.61) PTPN11RARBRARARARGPPARA
SCHEMBL9511120 0.86 PTPN11 (0.63) PTPN11RARBRARARARGPPARA
SCHEMBL9511529 0.86 PTPN11 (0.63) PTPN11RARBRARARARGPPARA
SCHEMBL8914026 0.85 PTPN11 (0.54) PTPN11RARBRARARARGPTPRC
SCHEMBL8914112 0.85 PTPN11 (0.62) PTPN11RARBRARAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5399290-A Liquid crystals with (polysila) alkyl wing groups CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1995-03-21 US disclosed