Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.63 |
| ▸ | RARB | P10826 | 8/20 | 0.56 |
| ▸ | RARA | P10276 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.52 |
| ▸ | RARG | P13631 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9511120 | 1.00 | PTPN11 (0.63) | PTPN11RARBRARATP53TSHR | |
| SCHEMBL11133724 | 0.96 | PTPN11 (0.61) | PTPN11RARBRARATP53TSHR | |
| SCHEMBL11138404 | 0.96 | PTPN11 (0.61) | PTPN11RARBRARATP53TSHR | |
| SCHEMBL9485504 | 0.91 | RARB (0.62) | PTPN11RARBRARARARG | |
| SCHEMBL7981006 | 0.90 | PTPN11 (0.66) | PTPN11RARBRARAPPARAPPARG | |
| SCHEMBL8044985 | 0.90 | PTPN11 (0.66) | PTPN11RARBRARAPPARAPPARG | |
| SCHEMBL9619553 | 0.90 | PTPN11 (0.66) | PTPN11RARBRARAPPARAPPARG | |
| SCHEMBL9193021 | 0.90 | PTPN11 (0.66) | PTPN11RARBRARAPPARAPPARG | |
| SCHEMBL28693936 | 0.90 | RARB (0.50) | PTPN11RARBRARAPPARAPPARG | |
| SCHEMBL9501744 | 0.89 | PTPN11 (0.64) | PTPN11RARBRARAPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187768-B1 | LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS | FERGASON JAMES L (US) | 1993-11-03 | — | — | EP | disclosed |
| US-5130828-A | Liquid crystal temperature sensor and materials | MANCHESTER R&D PARTNERSHIP (US) | 1992-07-14 | — | — | US | disclosed |
| US-4884877-A | Liquid crystal temperature sensor and materials utilizing microencapsulated liquid crystal | MANCHESTER R & D PARTNERSHIP (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0187768-A4 | LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS. | FERGASON JAMES L | 1989-03-09 | — | — | EP | disclosed |
| EP-0187768-A1 | LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS. | FERGASON JAMES L | 1986-07-23 | — | — | EP | disclosed |
| WO-1985005467-A1 | LIQUID CRYSTAL TEMPERATURE SENSOR AND MATERIALS | FERGASON JAMES L | 1985-12-05 | — | — | WO | disclosed |
| US-4385844-A | THERMOSENSITIVE NON-CHLOLESTERIC COMPOUND AND ALKYLBENZOATE LIQUID CRYSTALS | BECTON, DICKINSON AND COMPANY (US) | 1983-05-31 | — | — | US | disclosed |
| US-4296631-A | AND METHOD OF MODIFYING THE HYSTERETIC BEHAVIOR | BECTON, DICKINSON AND COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| US-4140016-A | CHOLESTERIC LIQUID CRYSTAL THERMOMETERS, BENZOIC ESTER DERIVATIVES | BECTON, DICKINSON AND COMPANY (US) | 1979-02-20 | — | — | US | disclosed |