Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 14/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150623 | 0.93 | ACE (0.46) | ACEMMP1MMP3 | |
| SCHEMBL9154585 | 0.92 | ACE (0.44) | ACEMMP1MMP3 | |
| SCHEMBL9155287 | 0.92 | ACE (0.44) | ACEMMP1MMP3 | |
| SCHEMBL9147365 | 0.92 | ACE (0.44) | ACEMMP1MMP3 | |
| SCHEMBL9150496 | 0.92 | ACE (0.44) | ACEMMP1MMP3 | |
| SCHEMBL9147468 | 0.92 | ACE (0.44) | ACEMMP1MMP3 | |
| SCHEMBL9148970 | 0.92 | ACE (0.44) | ACEMMP1MMP3 | |
| SCHEMBL9152069 | 0.91 | ACE (0.47) | ACEMMP1MMP3MME | |
| SCHEMBL9152667 | 0.90 | ACE (0.47) | ACEMMP1MMP3MME | |
| SCHEMBL9148349 | 0.88 | ACE (0.51) | ACEPIK3CDMMELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470848-A | Penetration enhancers for transdermal delivery of systemic agents | DISCOVERY THERAPEUTICS, INC. | 1995-11-28 | — | — | US | claimed |
| US-5472946-A | Topical administration of lincomycin, clindamycin, erthromycin and iododeoxyuridine on skin or mucuous membranes | DISCOVERY THERAPEUTICS, INC. | 1995-12-05 | — | — | US | disclosed |
| US-5470848-A | Penetration enhancers for transdermal delivery of systemic agents | DISCOVERY THERAPEUTICS, INC. | 1995-11-28 | — | — | US | disclosed |
| US-5444075-A | Penetration enhancers for transdermal delivery of systemic agents | MINASKANIAN GEVORK (US) | 1995-08-22 | — | — | US | disclosed |
| US-5234959-A | Omega-dialkylaminoalkanoic acids; drug delivery directly to the bloodstream | WHITBY RESEARCH, INC. (US) | 1993-08-10 | — | — | US | disclosed |
| US-5118692-A | Penetration enhances for transdermal delivery of systemic agents | WHITBY RESEARCH, INC. (US) | 1992-06-02 | — | — | US | disclosed |
| US-4996199-A | Penetration enhancers for transdermal delivery of systemic agents | WHITBY RESEARCH, INC. (US) | 1991-02-26 | — | — | US | disclosed |