Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.39 |
| ▸ | MMP3 | P08254 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155287 | 0.99 | ACE (0.44) | ACEMMP1MMP3PTPN1PTGER4 | |
| SCHEMBL9154585 | 0.99 | ACE (0.44) | ACEMMP1MMP3PTPN1PTGER4 | |
| SCHEMBL9148970 | 0.99 | ACE (0.44) | ACEMMP1MMP3PTPN1PTGER4 | |
| SCHEMBL9147468 | 0.99 | ACE (0.44) | ACEMMP1MMP3PTPN1PTGER4 | |
| SCHEMBL9150496 | 0.99 | ACE (0.44) | ACEMMP1MMP3PTPN1PTGER4 | |
| SCHEMBL9147365 | 0.99 | ACE (0.44) | ACEMMP1MMP3PTPN1PTGER4 | |
| SCHEMBL9152069 | 0.96 | ACE (0.47) | ACEMMP1MMP3 | |
| SCHEMBL9151384 | 0.93 | ACE (0.49) | ACEMMP1MMP3 | |
| SCHEMBL9152832 | 0.91 | MMP1 (0.45) | ACEMMP1MMP3 | |
| SCHEMBL9150123 | 0.91 | ACE (0.47) | ACEMMP1MMP3PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472946-A | Topical administration of lincomycin, clindamycin, erthromycin and iododeoxyuridine on skin or mucuous membranes | DISCOVERY THERAPEUTICS, INC. | 1995-12-05 | — | — | US | disclosed |
| US-5470848-A | Penetration enhancers for transdermal delivery of systemic agents | DISCOVERY THERAPEUTICS, INC. | 1995-11-28 | — | — | US | disclosed |
| US-5234959-A | Omega-dialkylaminoalkanoic acids; drug delivery directly to the bloodstream | WHITBY RESEARCH, INC. (US) | 1993-08-10 | — | — | US | disclosed |
| US-5118692-A | Penetration enhances for transdermal delivery of systemic agents | WHITBY RESEARCH, INC. (US) | 1992-06-02 | — | — | US | disclosed |
| US-4996199-A | Penetration enhancers for transdermal delivery of systemic agents | WHITBY RESEARCH, INC. (US) | 1991-02-26 | — | — | US | disclosed |