Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9152740 | 0.98 | CHRNA7 (0.38) | CHRNA7 | |
| SCHEMBL9147955 | 0.93 | CHRM2 (0.41) | — | |
| Hydrochloric Acid SCHEMBL9148283 | 0.91 | CHRM2 (0.40) | — | |
| Oxalic Acid SCHEMBL9152500 | 0.85 | CHRM2 (0.36) | — | |
| SCHEMBL9150768 | 0.80 | CHRNA7 (0.42) | CHRNA7 | |
| SCHEMBL9152478 | 0.78 | CHRNA7 (0.43) | CHRNA7 | |
| SCHEMBL9148716 | 0.76 | CHRNA7 (0.39) | CHRNA7 | |
| SCHEMBL9151124 | 0.76 | CHRNA7 (0.39) | CHRNA7 | |
| SCHEMBL9147373 | 0.76 | CHRNA7 (0.39) | CHRNA7 | |
| SCHEMBL9151298 | 0.76 | CHRNA7 (0.39) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405853-A | Potent muscarinic agonists having good central nervous system penetrability | MERCK SHARPE & DOHME LTD. (GB) | 1995-04-11 | — | — | US | claimed |
| EP-0307142-A1 | Thiadiazoles useful in the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-03-15 | — | — | EP | claimed |
| US-5405853-A | Potent muscarinic agonists having good central nervous system penetrability | MERCK SHARPE & DOHME LTD. (GB) | 1995-04-11 | — | — | US | disclosed |
| EP-0307142-A1 | Thiadiazoles useful in the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-03-15 | — | — | EP | disclosed |