Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9147996 | 0.92 | CHRM2 (0.51) | CHRM2 | |
| Oxalic Acid SCHEMBL9148594 | 0.91 | CHRNA7 (0.40) | CHRNA7CHRM2 | |
| Oxalic Acid SCHEMBL9151057 | 0.84 | CHRM2 (0.45) | CHRM2 | |
| SCHEMBL9150745 | 0.83 | CHRM2 (0.42) | CHRM2 | |
| SCHEMBL9152478 | 0.81 | CHRNA7 (0.43) | CHRNA7CHRM2 | |
| SCHEMBL9151124 | 0.80 | CHRNA7 (0.39) | CHRNA7CHRM2 | |
| SCHEMBL9151298 | 0.80 | CHRNA7 (0.39) | CHRNA7 | |
| SCHEMBL9147373 | 0.80 | CHRNA7 (0.39) | CHRNA7 | |
| SCHEMBL9152011 | 0.80 | CHRNA7 (0.39) | CHRNA7 | |
| SCHEMBL9147926 | 0.80 | CHRNA7 (0.39) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261763-B1 | Novel bridged bicyclic N-heterocycles | BEECHAM GROUP PLC (GB) | 1994-02-09 | — | — | EP | claimed |
| US-4968691-A | TREATMENT AND PREVENTION OF DEMENTIA | BEECHAM GROUP P.L.C. (GB) | 1990-11-06 | — | — | US | claimed |
| EP-0307142-A1 | Thiadiazoles useful in the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-03-15 | — | — | EP | claimed |
| EP-0261763-A1 | Novel bridged bicyclic N-heterocycles | BEECHAM GROUP PLC (GB) | 1988-03-30 | — | — | EP | claimed |
| US-5405853-A | Potent muscarinic agonists having good central nervous system penetrability | MERCK SHARPE & DOHME LTD. (GB) | 1995-04-11 | — | — | US | disclosed |
| EP-0307142-B1 | Thiadiazoles useful in the treatment of senile dementia | MERCK SHARP & DOHME (GB) | 1994-09-14 | — | — | EP | disclosed |
| US-4968691-A | TREATMENT AND PREVENTION OF DEMENTIA | BEECHAM GROUP P.L.C. (GB) | 1990-11-06 | — | — | US | disclosed |
| EP-0307142-A1 | Thiadiazoles useful in the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-03-15 | — | — | EP | disclosed |
| EP-0261763-A1 | Novel bridged bicyclic N-heterocycles | BEECHAM GROUP PLC (GB) | 1988-03-30 | — | — | EP | disclosed |