SCHEMBL9152175

SCHEMBL9152175

CC(O)C(C)COC(=O)C(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 3/20 0.50
PRKCD Q05655 1/20 0.33
MAPK1 P28482 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ELANE P08246 1/20 0.32
MMP8 P22894 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23037418 0.82 PRKCA (0.53) PRKCAPRKCDMAPK1POLBGAA
SCHEMBL23037415 0.82 PRKCA (0.53) PRKCAPRKCDMAPK1POLBGAA
SCHEMBL11963301 0.82 PRKCA (0.46) PRKCAPRKCDMAPK1POLBGAA
SCHEMBL13168170 0.79 PRKCA (0.55) PRKCAPRKCDMAPK1POLBGAA
SCHEMBL9463647 0.79 PRKCA (0.55) PRKCAPRKCDPOLBGAANPSR1
SCHEMBL685935 0.79 PRKCA (0.55) PRKCAPRKCDPOLBGAANPSR1
SCHEMBL18388530 0.77 PRKCA (0.53) PRKCAPRKCDMAPK1POLBGAA
SCHEMBL14508454 0.77 PRKCA (0.58) PRKCAPRKCDPOLBGAANPSR1
SCHEMBL26739643 0.77 PRKCA (0.48) PRKCAPRKCDMMP8
SCHEMBL13499125 0.76 PRKCA (0.52) PRKCAPRKCDMAPK1POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0351782-B1 Optically active compounds liquid crystal composition containing said compound, and liquid crystal optical modulator using said composition HITACHI LTD (JP) 1995-01-04 EP disclosed
US-5328643-A Electrooptic display, switches, modulators; physical and chemical stability and spontaneous polarization TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-07-12 US disclosed
EP-0351782-A2 Optically active compounds liquid crystal composition containing said compound, and liquid crystal optical modulator using said composition HITACHI, LTD. (JP) 1990-01-24 EP disclosed