Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9151670 | 0.86 | — | — | |
| SCHEMBL9151072 | 0.84 | DPP4 (0.35) | CHRM2 | |
| SCHEMBL9151515 | 0.82 | CHRM2 (0.35) | CHRM2CHRM1 | |
| SCHEMBL9148633 | 0.78 | CHRM2 (0.53) | CHRM2CHRM1 | |
| SCHEMBL9152478 | 0.76 | CHRNA7 (0.43) | CHRM2CHRM1 | |
| SCHEMBL9151214 | 0.73 | CHRM1 (0.43) | CHRM2CHRM1 | |
| SCHEMBL9369971 | 0.72 | CHRM2 (0.65) | CHRM2CHRM1 | |
| SCHEMBL9150021 | 0.71 | — | — | |
| SCHEMBL9149591 | 0.70 | DPP4 (0.32) | — | |
| SCHEMBL9149572 | 0.68 | CHRM2 (0.35) | CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405853-A | Potent muscarinic agonists having good central nervous system penetrability | MERCK SHARPE & DOHME LTD. (GB) | 1995-04-11 | — | — | US | claimed |
| EP-0307142-B1 | Thiadiazoles useful in the treatment of senile dementia | MERCK SHARP & DOHME (GB) | 1994-09-14 | — | — | EP | claimed |
| EP-0307142-A1 | Thiadiazoles useful in the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-03-15 | — | — | EP | claimed |
| US-5405853-A | Potent muscarinic agonists having good central nervous system penetrability | MERCK SHARPE & DOHME LTD. (GB) | 1995-04-11 | — | — | US | disclosed |
| EP-0307142-B1 | Thiadiazoles useful in the treatment of senile dementia | MERCK SHARP & DOHME (GB) | 1994-09-14 | — | — | EP | disclosed |
| EP-0307142-A1 | Thiadiazoles useful in the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-03-15 | — | — | EP | disclosed |