SCHEMBL9153087

SCHEMBL9153087

CN1C(C)(C)CC(OC(=O)NNC(=O)C(=O)NC2CC(C)(C)NC(C)(C)C2)CC1(C)C

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.39
POLB P06746 3/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
RECQL P46063 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.35
TSHR P16473 1/20 0.34
EZH2 Q15910 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9149131 0.95 GAA (0.39) GAAPOLBATML3MBTL1RECQL
SCHEMBL9149659 0.90 GAA (0.44) GAAPOLBATML3MBTL1RECQL
SCHEMBL10613796 0.84 GAA (0.40) GAAPOLBATML3MBTL1RECQL
SCHEMBL8944692 0.81 TSHR (0.35) GAAMEN1KMT2ATSHR
SCHEMBL9154314 0.79 GAA (0.52) GAAPOLBATML3MBTL1RECQL
SCHEMBL9150705 0.78 HDAC4 (0.37) GAAKMT2AMAPTTSHR
SCHEMBL9154360 0.75 MEN1 (0.49) GAAPOLBATML3MBTL1RECQL
SCHEMBL3295977 0.74 RECQL (0.57) GAAPOLBATML3MBTL1RECQL
SCHEMBL9420237 0.73 GAA (0.48) GAAPOLBATML3MBTL1RECQL
SCHEMBL10736707 0.73 GAA (0.36) GAAPOLBATML3MBTL1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5397821-A Light and heat stabilizers, low volatility ELFATOCHEM NORTH AMERICA, INC. (US) 1995-03-14 US disclosed
US-5338853-A N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-16 US disclosed