Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9002550 | 0.85 | HDAC4 (0.36) | HDAC4HDAC6MAPTGAAKDM4E | |
| SCHEMBL9456416 | 0.82 | EPHX2 (0.40) | HDAC4HDAC6GAAKDM4ESMN1; SMN2 | |
| SCHEMBL107837 | 0.81 | HDAC4 (0.36) | HDAC4HDAC6GAAKDM4ESMN1; SMN2 | |
| SCHEMBL9149131 | 0.81 | GAA (0.39) | MAPTGAAKMT2ATSHR | |
| SCHEMBL28889135 | 0.80 | HDAC4 (0.39) | HDAC4HDAC6HTTGAAKDM4E | |
| SCHEMBL8613134 | 0.80 | HDAC4 (0.39) | HDAC4HDAC6GAAKDM4EKMT2A | |
| SCHEMBL11046524 | 0.78 | MAOB (0.39) | HDAC4HDAC6MAPTHTTGAA | |
| SCHEMBL9156476 | 0.78 | THRB (0.35) | TSHR | |
| SCHEMBL13172679 | 0.78 | GAA (0.53) | MAPTHTTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL9153087 | 0.78 | GAA (0.39) | MAPTGAAKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397821-A | Light and heat stabilizers, low volatility | ELFATOCHEM NORTH AMERICA, INC. (US) | 1995-03-14 | — | — | US | disclosed |
| US-5338853-A | N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-08-16 | — | — | US | disclosed |
| EP-0434080-A1 | Derivatives of N-hals-substituted amic acid hydrazides | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1991-06-26 | — | — | EP | disclosed |