Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.55 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854382 | 1.00 | TRPA1 (0.55) | TRPA1RCE1MAPTHTTMMP9 | |
| SCHEMBL5278755 | 1.00 | TRPA1 (0.55) | TRPA1RCE1MAPTHTTMMP9 | |
| SCHEMBL19088657 | 0.85 | RCE1 (0.46) | TRPA1RCE1MAPTHTTMMP9 | |
| SCHEMBL11961368 | 0.83 | RCE1 (0.50) | TRPA1RCE1MAPTHTTMMP9 | |
| SCHEMBL11961365 | 0.83 | RCE1 (0.50) | TRPA1RCE1MAPTHTTMMP9 | |
| SCHEMBL1487082 | 0.83 | RCE1 (0.50) | TRPA1RCE1MAPTHTTMMP9 | |
| SCHEMBL11961367 | 0.83 | RCE1 (0.50) | TRPA1RCE1MAPTHTTMMP9 | |
| SCHEMBL11961366 | 0.83 | RCE1 (0.50) | TRPA1RCE1MAPTHTTMMP9 | |
| SCHEMBL16265939 | 0.83 | RCE1 (0.50) | TRPA1RCE1MAPTHTTMMP9 | |
| SCHEMBL16249927 | 0.82 | RCE1 (0.45) | TRPA1RCE1MAPTHTTMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351782-B1 | Optically active compounds liquid crystal composition containing said compound, and liquid crystal optical modulator using said composition | HITACHI LTD (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5328643-A | Electrooptic display, switches, modulators; physical and chemical stability and spontaneous polarization | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0351782-A2 | Optically active compounds liquid crystal composition containing said compound, and liquid crystal optical modulator using said composition | HITACHI, LTD. (JP) | 1990-01-24 | — | — | EP | disclosed |