SCHEMBL9154227

SCHEMBL9154227

CC1(C)CC(OC(=O)Oc2ccccc2)CC(C)(C)N1

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.64
EZH2 Q15910 6/20 0.48
TSHR P16473 3/20 0.48
POLB P06746 1/20 0.43
HTT P42858 1/20 0.41
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALOX15 P16050 1/20 0.40
USP2 O75604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14400354 0.81 GAA (0.51) GAATSHRPOLBHTTKMT2A
SCHEMBL9155535 0.81 TSHR (0.46) GAATSHRPOLBHTTKMT2A
SCHEMBL1312486 0.78 GAA (0.59) GAAEZH2TSHRPOLBHTT
SCHEMBL11445759 0.78 GAA (0.51) GAAEZH2TSHRPOLBHTT
SCHEMBL97715 0.78 GAA (1.00) GAAEZH2TSHRPOLBKMT2A
SCHEMBL16702066 0.78 GAA (0.56) GAAEZH2TSHRPOLBHTT
SCHEMBL674787 0.78 GAA (0.56) GAAEZH2TSHRPOLBHTT
Hydrochloric Acid SCHEMBL27993291 0.77 GAA (0.97) GAAEZH2TSHRPOLBKMT2A
SCHEMBL29793926 0.76 GAA (0.74) GAAEZH2TSHRPOLBHTT
SCHEMBL1556556 0.76 GAA (0.74) GAAEZH2TSHRPOLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5397821-A Light and heat stabilizers, low volatility ELFATOCHEM NORTH AMERICA, INC. (US) 1995-03-14 US disclosed
US-5338853-A N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-16 US disclosed