SCHEMBL9155535

SCHEMBL9155535

CN1C(C)(C)CC(OC(=O)Oc2ccccc2)CC1(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
KMT2A Q03164 3/20 0.46
CYP2D6 P10635 1/20 0.41
GAA P10253 5/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.39
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 2/20 0.37
NPSR1 Q6W5P4 1/20 0.36
SCN1A P35498 1/20 0.36
SCN2A Q99250 1/20 0.36
SCN3A Q9NY46 1/20 0.36
SLC6A3 Q01959 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM3 P20309 1/20 0.36
ESR1 P03372 1/20 0.36
HSD17B10 Q99714 1/20 0.36
POLB P06746 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14400354 0.88 GAA (0.51) TSHRKMT2ACYP2D6GAALMNA
SCHEMBL11845558 0.82 TSHR (0.41) TSHRKMT2ACYP2D6GAALMNA
SCHEMBL11845548 0.82 TSHR (0.44) TSHRKMT2ACYP2D6GAALMNA
SCHEMBL9154227 0.81 GAA (0.64) TSHRKMT2AGAAHTTPOLB
SCHEMBL294975 0.79 TSHR (0.70) TSHRKMT2AGAALMNAHTT
SCHEMBL6714702 0.79 TSHR (0.37) TSHRKMT2ACYP2D6GAALMNA
SCHEMBL17287083 0.76 SLC6A2 (0.50) TSHRKMT2ACYP2D6LMNASLC6A3
SCHEMBL9456353 0.75 BCHE (0.50) TSHRKMT2ALMNA
SCHEMBL10156072 0.74 KMT2A (0.44) TSHRKMT2ACYP2D6GAALMNA
SCHEMBL7766036 0.74 TSHR (0.35) TSHRKMT2ACYP2D6GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5397821-A Light and heat stabilizers, low volatility ELFATOCHEM NORTH AMERICA, INC. (US) 1995-03-14 US disclosed
US-5338853-A N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-16 US disclosed