Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | KDM5A | P29375 | 4/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.38 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330196 | 1.00 | SIGMAR1 (0.42) | SIGMAR1KDM5APHF8KDM2AKDM4C | |
| SCHEMBL330428 | 1.00 | — | — | |
| SCHEMBL9127640 | 1.00 | SIGMAR1 (0.42) | SIGMAR1KDM5APHF8KDM2AKDM4C | |
| SCHEMBL330352 | 0.97 | — | — | |
| SCHEMBL921566 | 0.89 | SIGMAR1 (0.50) | SIGMAR1KDM5APHF8KDM2AKDM4C | |
| SCHEMBL5534476 | 0.89 | SIGMAR1 (0.56) | SIGMAR1KDM5APHF8KDM2AKDM4C | |
| SCHEMBL5540630 | 0.89 | SIGMAR1 (0.56) | SIGMAR1KDM5APHF8KDM2AKDM4C | |
| SCHEMBL5540244 | 0.89 | SIGMAR1 (0.50) | SIGMAR1KDM5APHF8KDM2AKDM4C | |
| SCHEMBL135582 | 0.88 | — | — | |
| SCHEMBL1006169 | 0.87 | SIGMAR1 (0.60) | SIGMAR1KDM5APHF8KDM2AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407599-A | Cyclopropylaklyl or -alkenyl or heterocyclic compounds, process for their preparation and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-18 | — | — | US | disclosed |