Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1443826 | 1.00 | MAOA (0.62) | MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL1443825 | 1.00 | MAOA (0.62) | MAOAMAOBHDAC1HDAC2 | |
| Allylamine SCHEMBL11130182 | 0.90 | MAOA (0.53) | MAOAMAOB | |
| SCHEMBL10722870 | 0.80 | MAOB (0.51) | MAOB | |
| SCHEMBL10723499 | 0.79 | MAOA (0.59) | MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL8574266 | 0.79 | HDAC1 (0.59) | MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL5617716 | 0.79 | MAOA (0.59) | MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL5617714 | 0.79 | MAOA (0.59) | MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL16935823 | 0.78 | HDAC1 (0.53) | MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL10725020 | 0.78 | MAOB (0.50) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067105-B1 | ALLYL AMINE MAO INHIBITORS | MERRELL DOW FRANCE ET CIE (FR) | 1987-09-23 | — | — | EP | claimed |
| US-4454158-A | Allyl amine MAO inhibitors | MERRELL TORAUDE ET COMPAGNIE (FR) | 1984-06-12 | — | — | US | claimed |
| EP-0067105-A2 | Allyl amine MAO inhibitors | MERRELL DOW FRANCE ET CIE (FR) | 1982-12-15 | — | — | EP | claimed |
| US-9161922-B2 | Amine oxidase inhibitors | CASE WESTERN RESERVE UNIVERSITY (US) | 2015-10-20 | — | — | US | disclosed |
| EP-0330218-B1 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMA (US) | 1995-01-25 | — | — | EP | disclosed |
| US-5252608-A | Preventing the abnormal deposition of collagen by administering a halogenated allyl amines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-10-12 | — | — | US | disclosed |
| US-5182297-A | Thienylhaloallylamines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-01-26 | — | — | US | disclosed |
| US-5021456-A | Administering to treat dieseases of abnormal deposition of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-06-04 | — | — | US | disclosed |
| US-4965288-A | ABNORMAL COLLAGEN DEPOSITION | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-10-23 | — | — | US | disclosed |
| US-4943593-A | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-07-24 | — | — | US | disclosed |
| CN-1035497-A | The inhibitor of lysyloxidase | MERRELL DOW PHARMA (US) | 1989-09-13 | — | — | CN | disclosed |
| EP-0330218-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-08-30 | — | — | EP | disclosed |
| EP-0067105-B1 | ALLYL AMINE MAO INHIBITORS | MERRELL DOW FRANCE ET CIE (FR) | 1987-09-23 | — | — | EP | disclosed |
| US-4454158-A | Allyl amine MAO inhibitors | MERRELL TORAUDE ET COMPAGNIE (FR) | 1984-06-12 | — | — | US | disclosed |
| EP-0067105-A2 | Allyl amine MAO inhibitors | MERRELL DOW FRANCE ET CIE (FR) | 1982-12-15 | — | — | EP | disclosed |