Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RARB | P10826 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154119 | 1.00 | RAB9A (0.37) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL7872746 | 0.89 | KDM4E (0.41) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL7883709 | 0.89 | KDM4E (0.41) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL10000265 | 0.87 | NPC1 (0.51) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL9082199 | 0.85 | KDM4E (0.46) | RAB9AKDM4ENPC1SMN1; SMN2CYP3A4 | |
| SCHEMBL9082204 | 0.85 | KDM4E (0.46) | RAB9AKDM4ENPC1SMN1; SMN2CYP3A4 | |
| SCHEMBL10000263 | 0.83 | RAB9A (0.50) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL6947347 | 0.83 | RAB9A (0.51) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL6947951 | 0.83 | RAB9A (0.51) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL7877167 | 0.83 | NPC1 (0.51) | RAB9AKDM4ENPC1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5443754-A | Pyridylpyrimidines, a process for their preparation and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-22 | — | — | US | disclosed |