Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154778 | 0.90 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2TDP1 | |
| Ether SCHEMBL78444 | 0.82 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2TDP1PDK1 | |
| SCHEMBL18110 | 0.81 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2TDP1PDK1 | |
| Ether SCHEMBL107913 | 0.79 | ALDH1A1 (0.35) | ALDH1A1TDP1 | |
| Methylamine SCHEMBL28321012 | 0.78 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2TDP1PDK1 | |
| Water SCHEMBL29133266 | 0.78 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2TDP1PDK1 | |
| Ether SCHEMBL1786734 | 0.77 | HSD17B10 (0.33) | ALDH1A1TDP1 | |
| Ether SCHEMBL7880569 | 0.77 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2TDP1PDK1 | |
| SCHEMBL28044375 | 0.76 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL28240724 | 0.76 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2TDP1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452055-B1 | Surfaces with reduced protein interactions | HEWLETT PACKARD CO (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0377649-B1 | HALOGENATED SURFACE WITH REDUCED PROTEIN INTERACTION | Hewlett-Packard Company (US) | 1993-03-10 | — | — | EP | disclosed |
| US-5114768-A | Electrophoretic protein separation | HEWLETT-PACKARD COMPANY (US) | 1992-05-19 | — | — | US | disclosed |
| EP-0452055-A1 | Surfaces with reduced protein interactions | Hewlett-Packard Company (US) | 1991-10-16 | — | — | EP | disclosed |
| US-5006313-A | Halogenated surface with reduced protein interaction | HEWLETT-PACKARD COMPANY (US) | 1991-04-09 | — | — | US | disclosed |
| EP-0377649-A1 | HALOGENATED SURFACE WITH REDUCED PROTEIN INTERACTION. | HEWLETT PACKARD CO (US) | 1990-07-18 | — | — | EP | disclosed |
| WO-1989012225-A1 | HALOGENATED SURFACE WITH REDUCED PROTEIN INTERACTION | HEWLETT-PACKARD COMPANY (US) | 1989-12-14 | — | — | WO | disclosed |