Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7293954 | 0.78 | CYP3A4 (0.74) | CYP3A4CYP1A2CYP2C19CLEC4MKDM4E | |
| SCHEMBL7290898 | 0.76 | CYP1A2 (0.60) | CYP3A4CYP1A2CYP2C19CLEC4MDPP4 | |
| SCHEMBL3274638 | 0.76 | CYP1A2 (0.60) | CYP3A4CYP1A2CYP2C19CLEC4MKDM4E | |
| SCHEMBL2866771 | 0.76 | NR4A2 (0.74) | CYP1A2CYP2C19NR4A2KDM4EALDH1A1 | |
| SCHEMBL31451717 | 0.76 | NR4A2 (0.74) | CYP1A2CYP2C19NR4A2KDM4EALDH1A1 | |
| SCHEMBL7293120 | 0.74 | CYP1A2 (0.58) | CYP3A4CYP1A2CYP2C19CLEC4MDPP4 | |
| SCHEMBL31451463 | 0.73 | MAPT (0.67) | NR4A2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL7978838 | 0.73 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL1653889 | 0.72 | HPGD (0.60) | CYP3A4KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL5219479 | 0.71 | CA12 (0.45) | CYP3A4CYP1A2CYP2C19CLEC4MKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580713-B1 | METHOD FOR DYEING KERATIN FIBRES WITH AMINOINDOLES HAVING ALKALINE pH, AND COMPOSITIONS THEREFOR | OREAL (FR) | 1995-03-01 | — | — | EP | claimed |