Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | GLS | O94925 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801787 | 0.85 | ALDH1A1 (0.61) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL14560517 | 0.83 | ALDH1A1 (0.59) | ALDH1A1GLS | |
| SCHEMBL10215924 | 0.83 | ALDH1A1 (0.59) | ALDH1A1GLS | |
| SCHEMBL30242673 | 0.83 | ALDH1A1 (0.59) | ALDH1A1GLS | |
| SCHEMBL28989527 | 0.83 | ALDH1A1 (0.59) | ALDH1A1GLS | |
| SCHEMBL9157221 | 0.81 | ALDH1A1 (0.59) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL368756 | 0.80 | ALDH1A1 (0.65) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL13103211 | 0.79 | ALDH1A1 (0.63) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL9485569 | 0.79 | ALDH1A1 (0.57) | ALDH1A1GLSMAPTNPSR1CASP3 | |
| SCHEMBL11682769 | 0.79 | ALDH1A1 (0.55) | ALDH1A1GLSMAPTNPSR1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402312-B1 | P-substituted propane-phosphinic acid compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | disclosed |
| US-5190934-A | Treatment of cognitive and memory disorders | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| EP-0402312-A2 | P-substituted propane-phosphinic acid compounds | CIBA-GEIGY AG (CH) | 1990-12-12 | — | — | EP | disclosed |