Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ERN1 | O75460 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.50 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5882846 | 0.89 | ALDH1A1 (0.65) | KDM4ERAB9AERN1ALDH1A1TRIM24 | |
| SCHEMBL1808738 | 0.87 | KDM4E (0.53) | KDM4ERAB9AERN1ALDH1A1TRIM24 | |
| SCHEMBL28676135 | 0.85 | ALDH1A1 (0.54) | KDM4ERAB9AERN1ALDH1A1TRIM24 | |
| SCHEMBL27500190 | 0.85 | KDM4E (0.58) | KDM4ERAB9AERN1ALDH1A1TRIM24 | |
| SCHEMBL16851803 | 0.85 | BACE1 (0.46) | KDM4ERAB9AERN1ALDH1A1TUBB1 | |
| SCHEMBL20488634 | 0.83 | KDM4E (0.59) | KDM4ERAB9AERN1ALDH1A1TRIM24 | |
| SCHEMBL3221472 | 0.82 | BACE1 (0.58) | KDM4ERAB9AERN1ALDH1A1TRIM24 | |
| SCHEMBL2560931 | 0.82 | KDM4E (0.55) | KDM4ERAB9AERN1ALDH1A1TRIM24 | |
| SCHEMBL14448836 | 0.81 | KDM4E (0.51) | KDM4ERAB9AERN1ALDH1A1TRIM24 | |
| SCHEMBL5882010 | 0.81 | KDM4E (0.64) | KDM4ERAB9AERN1ALDH1A1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385922-A | Cardiovascular and gastrointestinal disorders; antiischemic and cardiotonic agents | CEDONA PHARMACEUTICALS B.V. (NL) | 1995-01-31 | — | — | US | disclosed |
| EP-0547104-A1 | THIAZOLIDIN DERIVATIVES | CEDONA PHARMACEUTICALS B.V. (NL) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992004337-A1 | THIAZOLIDIN DERIVATIVES | CEDONA PHARMACEUTICALS BV (NL) | 1992-03-19 | — | — | WO | disclosed |
| US-4778818-A | VISION AND SKIN DISORDERS | MERCK & CO., INC. (US) | 1988-10-18 | — | — | US | disclosed |
| US-4686235-A | TOPICAL | MERCK & CO., INC. (US) | 1987-08-11 | — | — | US | disclosed |
| US-4053415-A | UNSATURATED POLYESTER ETHER HAVING A PHOTOCROSSLINKABLE MOIETY | FUJI PHOTO FILM CO., LTD. (JA) | 1977-10-11 | — | — | US | disclosed |