SCHEMBL9155278

SCHEMBL9155278

COc1ccc(Oc2nc(Cl)nc(Oc3ccc(OC)cc3)n2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.79
MEN1 O00255 1/20 0.79
KMT2A Q03164 1/20 0.79
L3MBTL1 Q9Y468 2/20 0.60
MAPT P10636 3/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HPGD P15428 1/20 0.48
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
LTA4H P09960 2/20 0.45
KDM4E B2RXH2 1/20 0.44
OPRM1 P35372 1/20 0.42
OPRL1 P41146 1/20 0.42
RAB9A P51151 1/20 0.42
MERTK Q12866 1/20 0.41
PARP10 Q53GL7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10411682 0.96 ALDH1A1 (0.72) ALDH1A1MEN1KMT2AL3MBTL1MAPT
SCHEMBL8864442 0.89 ALDH1A1 (1.00) ALDH1A1MEN1KMT2AL3MBTL1MAPT
SCHEMBL10636931 0.84 ALDH1A1 (0.56) ALDH1A1MEN1KMT2AL3MBTL1MAPT
SCHEMBL23999203 0.83 ALDH1A1 (0.86) ALDH1A1MEN1KMT2AL3MBTL1MAPT
SCHEMBL32688290 0.82 MEN1 (0.53) ALDH1A1MEN1KMT2AL3MBTL1MAPT
SCHEMBL11859472 0.82 MEN1 (0.53) ALDH1A1MEN1KMT2AL3MBTL1MAPT
SCHEMBL10639417 0.79 ALDH1A1 (0.50) ALDH1A1MEN1KMT2AL3MBTL1MAPT
SCHEMBL17795954 0.79 MEN1 (0.52) ALDH1A1MEN1KMT2AL3MBTL1LTA4H
SCHEMBL9151535 0.79 ALDH1A1 (0.48) ALDH1A1MEN1KMT2AL3MBTL1MAPT
SCHEMBL17563555 0.78 MEN1 (0.50) ALDH1A1MEN1KMT2AL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0386544-B1 Aryloxytriazine-capped polyphenylene ethers and method for their preparation GEN ELECTRIC (US) 1995-01-18 EP disclosed
EP-0386545-B1 Polyphenylene ether-polyamide compositions from aryloxytriazine-capped polyphenylene ethers GEN ELECTRIC (US) 1994-01-26 EP disclosed
US-RE34364-E Polyphenylene ether-polyamide compositions from aryloxytriazine-capped polyphenylene ethers GENERAL ELECTRIC COMPANY (US) 1993-08-31 US disclosed
EP-0550209-A2 Polyphenylene ether resins GENERAL ELECTRIC COMPANY (US) 1993-07-07 EP disclosed
US-5034527-A Chemical intermediates for polycarbonates GENERAL ELECTRIC COMPANY (US) 1991-07-23 US disclosed
US-5030693-A Copolymer compositions prepared from triazine derivatives of polycarbonates GENERAL ELECTRIC COMPANY (US) 1991-07-09 US disclosed
US-5001201-A Aryloxytriazine-capped polyphenylene ethers and method for their preparation GENERAL ELECTRIC COMPANY (US) 1991-03-19 US disclosed
US-4997885-A Polyphenylene ether-polyamide compositions from aryloxytriazine-capped polyphenylene ethers GENERAL ELECTRIC COMPANY (US) 1991-03-05 US disclosed
EP-0386544-A2 Aryloxytriazine-capped polyphenylene ethers and method for their preparation GENERAL ELECTRIC COMPANY (US) 1990-09-12 EP disclosed
EP-0386545-A2 Polyphenylene ether-polyamide compositions from aryloxytriazine-capped polyphenylene ethers GENERAL ELECTRIC COMPANY (US) 1990-09-12 EP disclosed
US-4247692-A STABILIZERS AGAINST ULTRAVIOLET RADIATION; FILMS; COATINGS AKZONA INCORPORATED (US) 1981-01-27 US disclosed