Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844446 | 0.79 | — | — | |
| SCHEMBL4199862 | 0.79 | — | — | |
| SCHEMBL14844395 | 0.77 | — | — | |
| SCHEMBL1966773 | 0.77 | — | — | |
| SCHEMBL8010825 | 0.77 | — | — | |
| SCHEMBL4885932 | 0.74 | NOS3 (0.34) | NOS3NOS2NOS1 | |
| SCHEMBL1706799 | 0.73 | NOS3 (0.33) | NOS3NOS2NOS1 | |
| SCHEMBL5902532 | 0.70 | CYP1A2 (0.45) | NOS3NOS2NOS1 | |
| SCHEMBL414019 | 0.68 | — | — | |
| SCHEMBL15637844 | 0.68 | NOS3 (0.30) | NOS3NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422334-A | Isoxazolone dyes having high molar extinction coefficients, high sublimation and diffusion rates and high spectral side absorptions | AGFA-GEVAERT N.V. (BE) | 1995-06-06 | — | — | US | disclosed |