Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12836119 | 0.94 | FFAR1 (0.50) | MEN1KMT2ACYP2C19FFAR1MITF | |
| SCHEMBL17761209 | 0.94 | FFAR1 (0.50) | MEN1KMT2ACYP2C19FFAR1MITF | |
| SCHEMBL9153276 | 0.86 | FFAR1 (0.60) | MEN1KMT2ACYP2C19FFAR1MITF | |
| SCHEMBL9150014 | 0.84 | FFAR1 (0.44) | MEN1KMT2ACYP2C19FFAR1MITF | |
| SCHEMBL27396213 | 0.83 | MEN1 (0.46) | MEN1KMT2AFFAR1MITFEPHX1 | |
| SCHEMBL8007179 | 0.83 | KMT2A (0.67) | MEN1KMT2ACYP2C19FFAR1MITF | |
| SCHEMBL28469916 | 0.79 | FFAR1 (0.51) | MEN1KMT2ACYP2C19FFAR1MITF | |
| SCHEMBL9413683 | 0.79 | MEN1 (0.40) | MEN1KMT2ACYP2C19FFAR1MITF | |
| SCHEMBL9153116 | 0.78 | SLC6A2 (0.42) | MEN1KMT2ACYP2C19MITFHTR1E | |
| SCHEMBL17761361 | 0.78 | FFAR1 (0.50) | MEN1KMT2ACYP2C19FFAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414008-A | Hypotensive and antiatherosclerotic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |
| EP-0578002-A1 | Imidazolyl substituted phenylpropionic and cinnamic acid derivatives | BAYER AG (DE) | 1994-01-12 | — | — | EP | disclosed |