Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153276 | 0.86 | FFAR1 (0.60) | FFAR1HTR1ES1PR3MEN1KMT2A | |
| SCHEMBL9155662 | 0.84 | MEN1 (0.47) | FFAR1HTR1ES1PR3MEN1KMT2A | |
| SCHEMBL9153434 | 0.82 | NPC1 (0.42) | FFAR1HTR1ES1PR3MEN1KMT2A | |
| SCHEMBL27396973 | 0.82 | MEN1 (0.42) | FFAR1MEN1KMT2AMITFRAB9A | |
| SCHEMBL9413683 | 0.79 | MEN1 (0.40) | FFAR1HTR1ES1PR3MEN1KMT2A | |
| SCHEMBL9153116 | 0.78 | SLC6A2 (0.42) | HTR1ES1PR3MEN1KMT2AMITF | |
| SCHEMBL17761209 | 0.78 | FFAR1 (0.50) | FFAR1HTR1ES1PR3MEN1KMT2A | |
| SCHEMBL12836119 | 0.78 | FFAR1 (0.50) | FFAR1HTR1ES1PR3MEN1KMT2A | |
| SCHEMBL2439425 | 0.76 | NPC1 (0.42) | FFAR1MEN1KMT2AMITFTSHR | |
| SCHEMBL4249915 | 0.73 | FFAR1 (0.60) | FFAR1MEN1KMT2AMITFTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414008-A | Hypotensive and antiatherosclerotic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |
| EP-0578002-A1 | Imidazolyl substituted phenylpropionic and cinnamic acid derivatives | BAYER AG (DE) | 1994-01-12 | — | — | EP | disclosed |