Tetrachloroethylene

Tetrachloroethylene

SCHEMBL9155697

ClC(Cl)=C(Cl)Cl.FC(F)(F)Cl

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrachloroethylene SCHEMBL10778928 0.82 TSHR (0.42) TSHR
Tetrachloroethylene SCHEMBL10783584 0.82 TSHR (0.42) TSHR
Dichlorodifluoromethane SCHEMBL28682201 0.78
Tetrachloroethylene SCHEMBL9722579 0.78 TSHR (0.62) TSHR
SCHEMBL8132063 0.78
SCHEMBL14785538 0.78
SCHEMBL27896 0.78
Tetrachloroethylene SCHEMBL5313853 0.74 TSHR (0.56) TSHR
Methyl Alcohol SCHEMBL10769228 0.74
Tetrachloroethylene SCHEMBL1405452 0.73 ALDH1A1 (0.47) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0632748-A1 CATALYST FOR PROMOTING HALOGEN EXCHANGE BTG INTERNATIONAL LIMITED (GB) 1995-01-11 EP disclosed
WO-1993019845-A1 CATALYST FOR PROMOTING HALOGEN EXCHANGE BRITISH TECHNOLOGY GROUP LTD (GB) 1993-10-14 WO disclosed