SCHEMBL9155960

SCHEMBL9155960

O=C(O)[C@H]1O[C@@H](n2cnc3c(O)ncnc32)C(O)C1O

nearest known ligand 0.76

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AHCY P23526 4/20 0.76
HIF1A Q16665 1/20 0.76
TMEM97 Q5BJF2 1/20 0.76
SIGMAR1 Q99720 1/20 0.76
ADORA2A P29274 10/20 0.71
ADORA2B P29275 10/20 0.71
HSP90B1 P14625 2/20 0.61
ADORA3 P0DMS8 3/20 0.58
ADORA1 P30542 2/20 0.57
TSHR P16473 1/20 0.57
LMNA P02545 1/20 0.57
THRB P10828 1/20 0.57
BLM P54132 1/20 0.57
KMT2A Q03164 1/20 0.57
HSP90AA1 P07900 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9155975 1.00 AHCY (0.76) AHCYHIF1ATMEM97SIGMAR1ADORA2A
SCHEMBL30555907 1.00 AHCY (0.76) AHCYHIF1ATMEM97SIGMAR1ADORA2A
Phosphoric Acid SCHEMBL27939253 0.95 AHCY (0.69) AHCYHIF1ATMEM97SIGMAR1ADORA2A
Phosphoric Acid SCHEMBL28250574 0.92 AHCY (0.65) AHCYHIF1ATMEM97SIGMAR1ADORA2A
SCHEMBL11037248 0.88 AHCY (0.59) AHCYHIF1ATMEM97SIGMAR1ADORA2A
SCHEMBL29238934 0.88 AHCY (0.59) AHCYHIF1ATMEM97SIGMAR1ADORA2A
SCHEMBL3906720 0.88 AHCY (0.59) AHCYHIF1ATMEM97SIGMAR1ADORA2A
5'-Carboxy Adenosine SCHEMBL2117314 0.86 AHCY (1.00) AHCYHIF1ATMEM97SIGMAR1ADORA2A
SCHEMBL13382546 0.86 AHCY (0.74) AHCYHIF1ATMEM97SIGMAR1ADORA2A
5'-Carboxy Adenosine SCHEMBL29376409 0.86 AHCY (1.00) AHCYHIF1ATMEM97SIGMAR1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0353311-B1 NUCLEOSIDE OXIDASE AND ANALYTICAL METHOD USING SAME OTSUKA FOOD CO LTD (JP) 1995-01-18 EP disclosed
US-5156955-A Used as enzyme for catalyzing oxidation reaction of nucleoside OTSUKA FOODS CO., LTD. (JP) 1992-10-20 US disclosed
EP-0353311-A1 NUCLEOSIDE OXIDASE AND ANALYTICAL METHOD USING SAME OTSUKA FOODS CO., LTD. (JP) 1990-02-07 EP disclosed