SCHEMBL9156352

SCHEMBL9156352

O=[N+]([O-])c1ccc(C(OC(c2ccc([N+](=O)[O-])cc2)C2CO2)C2CO2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
MAPT P10636 4/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
PHLPP2 Q6ZVD8 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KDM4E B2RXH2 1/20 0.38
PTPN2 P17706 1/20 0.38
PTPN1 P18031 1/20 0.38
ACHE P22303 1/20 0.37
HSD17B10 Q99714 1/20 0.37
GAA P10253 2/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
SLC6A3 Q01959 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28531376 0.80 SLC6A2 (0.45) ALDH1A1CYP3A4MAPK1KDM4EMEN1
SCHEMBL1299034 0.78 ALDH1A1 (0.49) ALDH1A1MAPTKDM4EGAAMEN1
SCHEMBL651374 0.78 ALDH1A1 (0.49) ALDH1A1MAPTKDM4EGAAMEN1
SCHEMBL28592383 0.78 ALDH1A1 (0.49) ALDH1A1MAPTKDM4EGAAMEN1
SCHEMBL9232753 0.73 IDO1 (0.42) ALDH1A1MAPTTSHRLMNAPOLB
SCHEMBL10488435 0.73 CYP2A6 (0.32)
SCHEMBL151181 0.72 IDO1 (0.44) TSHRSLC6A3
SCHEMBL30196531 0.71 ALDH1A1 (0.44) ALDH1A1CYP1A2TSHRTDP1L3MBTL1
SCHEMBL28956290 0.71 ALDH1A1 (0.44) ALDH1A1CYP1A2TSHRTDP1L3MBTL1
SCHEMBL7867600 0.70 EPHX1 (0.41) ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109306051-B Preparation method of colorless and transparent epoxy resin normal-temperature curing agent 山东天茂新材料科技股份有限公司 2020-09-29 CN disclosed
US-5410043-A Chemical intermediate for metal complexes SCHERING AKTIENGESELLSCHAFT (DE) 1995-04-25 US disclosed
US-4258045-A 2,4-DIAMINO-5-((ARYLALKOXY)BENZYL)-PYRIMIDINES AS ANTIBACTERIAL, ANTIPROTOZOAL AND ANTITUMOR AGENTS MERCK & CO., INC. (US) 1981-03-24 US disclosed
US-4029583-A GLYCIDYL ETHERS, SILANE COUPLER PURDUE RESEARCH FOUNDATION (US) 1977-06-14 US disclosed
US-3953604-A INHALATION, ANTI-ASTHMA MILES LABORATORIES, INC. (US) 1976-04-27 US disclosed