SCHEMBL9156486

SCHEMBL9156486

[CH2]CCOc1c(C)c2ccccc2oc1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.46
ACHE P22303 3/20 0.41
ALDH1A1 P00352 4/20 0.41
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
MAOB P27338 2/20 0.40
KCNA3 P22001 1/20 0.40
MAOA P21397 1/20 0.40
MAPT P10636 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP2C9 P11712 3/20 0.39
ADORA3 P0DMS8 1/20 0.39
GAA P10253 2/20 0.39
HSD17B10 Q99714 2/20 0.39
MAPK1 P28482 2/20 0.39
USP2 O75604 1/20 0.39
HPGD P15428 1/20 0.39
ABCB11 O95342 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30093459 0.84 KDM4E (0.49) KDM4EACHEALDH1A1CA12CA9
SCHEMBL27858069 0.84 KDM4E (0.45) KDM4EACHEALDH1A1CA12CA9
SCHEMBL28217805 0.84 FAAH (0.46) KDM4EALDH1A1KCNA3LMNATSHR
SCHEMBL9956829 0.83 KDM4E (0.50) KDM4EALDH1A1MAPTKMT2ACYP2C9
SCHEMBL30704393 0.83 KDM4E (0.44) KDM4EACHEALDH1A1CA12CA9
SCHEMBL30093463 0.82 KDM4E (0.47) KDM4EACHEALDH1A1CA12CA9
SCHEMBL31039502 0.82 KDM4E (0.47) KDM4EACHEALDH1A1CA12CA9
SCHEMBL31039501 0.82 KDM4E (0.47) KDM4EACHEALDH1A1CA12CA9
SCHEMBL30093462 0.82 KDM4E (0.47) KDM4EACHEALDH1A1CA12CA9
SCHEMBL8651414 0.81 KDM4E (0.42) KDM4EACHEALDH1A1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0455384-B1 Curable fluorescent organopolysiloxane compositions DOW CORNING (US) 1995-01-25 EP disclosed
US-5118776-A Durable marker; adhesive, release agent DOW CORNING CORPORATION (US) 1992-06-02 US disclosed
US-5107008-A Having a pendant dansyl or methylcoumarin nucleus; adhesive release coatings DOW CORNING CORPORATION (US) 1992-04-21 US disclosed
EP-0455384-A2 Curable fluorescent organopolysiloxane compositions DOW CORNING CORPORATION (US) 1991-11-06 EP disclosed