SCHEMBL9157237

SCHEMBL9157237

O=c1cc(-c2ccc(Cl)cc2)c2ccccc2n1CCCN1CCC(c2c[nH]c3ccccc23)CC1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 4/20 0.57
HTR1A P08908 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9158011 0.93 ADRA1D (0.61) ADRA1D
SCHEMBL9157951 0.91 ADRA1D (0.57) ADRA1DHTR1A
SCHEMBL9156488 0.83 ADRA1D (0.63) ADRA1D
SCHEMBL9156509 0.82 ADRA1D (0.59) ADRA1D
SCHEMBL9158443 0.79 ADRA1D (0.65) ADRA1D
SCHEMBL464522 0.77 ADRA1D (0.65) ADRA1D
SCHEMBL11038162 0.77 ADRA1D (0.68) ADRA1D
Hydrochloric Acid SCHEMBL7259157 0.77 ADRA1D (0.90) ADRA1D
SCHEMBL11245089 0.76 ADRA1D (0.67) ADRA1D
Hydrochloric Acid SCHEMBL11037928 0.76 ADRA1D (0.69) ADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5457099-A Carbostyril derivatives and antiallergic agent SAWAI PHARMACEUTICAL CO., LTD. (JP) 1995-10-10 US disclosed
EP-0577325-A1 Carbostyril derivatives and antiallergic agent SAWAI PHARMACEUTICAL CO., LTD. (JP) 1994-01-05 EP disclosed