Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9157583 | 1.00 | SPHK1 (0.46) | SPHK1SPHK2ACACB | |
| SCHEMBL9157412 | 0.91 | SPHK1 (0.54) | SPHK1SPHK2 | |
| SCHEMBL9157402 | 0.91 | SPHK1 (0.54) | SPHK1SPHK2 | |
| SCHEMBL9161349 | 0.90 | SPHK1 (0.59) | SPHK1SPHK2 | |
| SCHEMBL9161339 | 0.90 | SPHK1 (0.59) | SPHK1SPHK2 | |
| SCHEMBL9874841 | 0.89 | SPHK1 (0.52) | SPHK1SPHK2 | |
| SCHEMBL9874845 | 0.89 | SPHK1 (0.52) | SPHK1SPHK2 | |
| SCHEMBL9158730 | 0.88 | SPHK1 (0.38) | SPHK1SPHK2ACACB | |
| SCHEMBL9158726 | 0.88 | SPHK1 (0.38) | SPHK1SPHK2ACACB | |
| SCHEMBL9154858 | 0.82 | CYP2C9 (0.46) | SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-B1 | PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5205962-A | Stable liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-27 | — | — | US | disclosed |