Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.52 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874841 | 1.00 | SPHK1 (0.52) | SPHK1SPHK2KDM4EMEN1USP2 | |
| SCHEMBL9161349 | 0.93 | SPHK1 (0.59) | SPHK1SPHK2KDM4EMEN1USP2 | |
| SCHEMBL9161339 | 0.93 | SPHK1 (0.59) | SPHK1SPHK2KDM4EMEN1USP2 | |
| SCHEMBL9157412 | 0.91 | SPHK1 (0.54) | SPHK1SPHK2 | |
| SCHEMBL9157402 | 0.91 | SPHK1 (0.54) | SPHK1SPHK2 | |
| SCHEMBL9157583 | 0.89 | SPHK1 (0.46) | SPHK1SPHK2 | |
| SCHEMBL9157571 | 0.89 | SPHK1 (0.46) | SPHK1SPHK2 | |
| SCHEMBL9158730 | 0.86 | SPHK1 (0.38) | SPHK1SPHK2KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL9158726 | 0.86 | SPHK1 (0.38) | SPHK1SPHK2KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL9874452 | 0.84 | SPHK1 (0.38) | SPHK1SPHK2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991004248-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |