Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8860020 | 0.93 | ALDH1A1 (0.55) | ALDH1A1POLBLMNAKDM4EMEN1 | |
| SCHEMBL9154018 | 0.91 | ALDH1A1 (0.50) | ALDH1A1POLBLMNAKDM4EMEN1 | |
| SCHEMBL9152697 | 0.91 | ALDH1A1 (0.50) | ALDH1A1POLBLMNAKDM4EMEN1 | |
| SCHEMBL9156646 | 0.89 | ALDH1A1 (0.46) | ALDH1A1POLBLMNAKDM4EMEN1 | |
| SCHEMBL9158369 | 0.88 | ALDH1A1 (0.52) | ALDH1A1POLBLMNAKDM4EMEN1 | |
| SCHEMBL9159392 | 0.86 | ALDH1A1 (0.55) | ALDH1A1POLBMEN1KMT2ANPC1 | |
| SCHEMBL9153600 | 0.85 | ALDH1A1 (0.45) | ALDH1A1POLBLMNAKDM4EMEN1 | |
| SCHEMBL9132786 | 0.85 | ALDH1A1 (0.44) | ALDH1A1DRD4POLBLMNAKDM4E | |
| SCHEMBL9154498 | 0.85 | ALDH1A1 (0.47) | ALDH1A1POLBLMNAKDM4EMEN1 | |
| SCHEMBL9133896 | 0.83 | ALDH1A1 (0.47) | ALDH1A1POLBLMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |