Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | TPMT | P51580 | 1/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1466344 | 0.79 | MAPT (0.43) | TDP1CYP3A4MAPTCA1CA2 | |
| SCHEMBL2919054 | 0.72 | TDP1 (0.52) | TDP1CYP3A4MAPTPDE4BPDE4A | |
| SCHEMBL28644340 | 0.70 | TDP1 (0.39) | TDP1CYP3A4MAPTPDE4BPDE4A | |
| SCHEMBL29403778 | 0.68 | TDP1 (0.52) | TDP1CYP3A4MAPTPDE4BPDE4A | |
| SCHEMBL69925 | 0.68 | TDP1 (0.52) | TDP1CYP3A4MAPTPDE4BPDE4A | |
| SCHEMBL1192886 | 0.67 | CA2 (0.43) | TDP1CYP3A4MAPTCA1CA2 | |
| SCHEMBL5475365 | 0.65 | TDP1 (0.39) | TDP1CYP3A4MAPTPDE4BPDE4A | |
| SCHEMBL1299477 | 0.65 | MAPT (0.43) | TDP1CYP3A4MAPTCA1CA2 | |
| SCHEMBL16056542 | 0.65 | CYP3A4 (0.48) | TDP1CYP3A4MAPTCA1CA2 | |
| SCHEMBL20476840 | 0.64 | TPMT (0.43) | TDP1CYP3A4MAPTPDE4BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526302-B1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | OREAL (FR) | 1995-03-01 | — | — | EP | claimed |
| EP-0526302-A1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | L'OREAL (FR) | 1993-02-03 | — | — | EP | claimed |
| EP-0526302-B1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | OREAL (FR) | 1995-03-01 | — | — | EP | disclosed |
| EP-0526302-A1 | Depigmentation composition containing derivatives of (2,5-dihydroxyphenyl)-carboxylica | L'OREAL (FR) | 1993-02-03 | — | — | EP | disclosed |