Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158223 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CA12CA9KMT2AMEN1 | |
| SCHEMBL8860020 | 0.83 | ALDH1A1 (0.55) | ALDH1A1LMNATP53CA12CA9 | |
| SCHEMBL9159771 | 0.83 | CA12 (0.57) | ALDH1A1CA12CA9KMT2AMEN1 | |
| SCHEMBL8860030 | 0.83 | CA12 (0.60) | ALDH1A1CA12CA9KMT2AMEN1 | |
| SCHEMBL9471262 | 0.80 | ALDH1A1 (0.51) | ALDH1A1TP53CA12CA9KMT2A | |
| SCHEMBL5292795 | 0.79 | ALDH1A1 (0.61) | ALDH1A1CA12CA9KMT2AMEN1 | |
| SCHEMBL9152697 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNATP53CA12CA9 | |
| SCHEMBL9154018 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNATP53CA12CA9 | |
| SCHEMBL9158815 | 0.78 | MEN1 (0.50) | ALDH1A1CA12CA9KMT2AMEN1 | |
| SCHEMBL9158369 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNATP53CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |