Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155935 | 0.92 | PPIB (0.44) | PPIBMAPTSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL9158391 | 0.91 | HPSE (0.46) | PPIBMAPTRAB9AMEN1KMT2A | |
| SCHEMBL29422582 | 0.91 | HPSE (0.46) | PPIBMAPTRAB9AMEN1KMT2A | |
| SCHEMBL9159956 | 0.90 | PPIB (0.43) | PPIBMAPTSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL9158333 | 0.89 | GAA (0.46) | PPIBMAPTRAB9AMEN1KMT2A | |
| SCHEMBL9155523 | 0.89 | PPIB (0.42) | PPIBMAPTSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL9155529 | 0.89 | PPIB (0.42) | PPIBMAPTSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL9154435 | 0.88 | MAPT (0.44) | PPIBMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9155456 | 0.88 | PPIB (0.41) | PPIBMAPTSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL9153916 | 0.87 | PPIB (0.41) | PPIBMAPTSMN1; SMN2RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |