Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155935 | 0.92 | PPIB (0.44) | PPIBALDH1A1GAAALOX15CNR1 | |
| SCHEMBL9158333 | 0.91 | GAA (0.46) | PPIBALDH1A1GAAALOX15CNR1 | |
| SCHEMBL9135316 | 0.91 | KMT2A (0.48) | ALDH1A1CNR1KMT2AMEN1NPC1 | |
| SCHEMBL9158010 | 0.90 | PPIB (0.44) | PPIBALDH1A1GAAALOX15KMT2A | |
| SCHEMBL9155529 | 0.89 | PPIB (0.42) | PPIBALDH1A1GAAALOX15CNR1 | |
| SCHEMBL29422582 | 0.89 | HPSE (0.46) | PPIBALDH1A1GAAALOX15KMT2A | |
| SCHEMBL9158391 | 0.89 | HPSE (0.46) | PPIBALDH1A1GAAALOX15KMT2A | |
| SCHEMBL9155523 | 0.87 | PPIB (0.42) | PPIBALDH1A1GAAALOX15CNR1 | |
| SCHEMBL9154499 | 0.87 | ALDH1A1 (0.44) | PPIBALDH1A1GAAALOX15KMT2A | |
| SCHEMBL9155456 | 0.86 | PPIB (0.41) | PPIBALDH1A1GAAALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |