Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CPN1 | P15169 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | DDX3X | O00571 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158042 | 1.00 | KMT2A (0.47) | KMT2ACPN1CPB2ALDH1A1PTGS1 | |
| SCHEMBL3682275 | 0.89 | KMT2A (0.53) | KMT2APTGS1PTGS2MEN1L3MBTL1 | |
| SCHEMBL31478060 | 0.84 | PTGS1 (0.60) | KMT2ACPN1CPB2ALDH1A1PTGS1 | |
| SCHEMBL3402993 | 0.84 | PTGS1 (0.60) | KMT2ACPN1CPB2ALDH1A1PTGS1 | |
| SCHEMBL2194032 | 0.83 | CPN1 (0.47) | CPN1CPB2ALDH1A1ADRB2ADRB1 | |
| SCHEMBL9019965 | 0.82 | KMT2A (0.47) | KMT2APTGS1PTGS2MEN1HSD17B10 | |
| SCHEMBL9432428 | 0.82 | KMT2A (0.47) | KMT2APTGS1PTGS2MEN1HSD17B10 | |
| SCHEMBL5285167 | 0.82 | HIF1A (0.49) | KMT2AALDH1A1PTGS1PTGS2ADRB2 | |
| SCHEMBL5285160 | 0.82 | HIF1A (0.49) | KMT2AALDH1A1PTGS1PTGS2ADRB2 | |
| SCHEMBL7336123 | 0.81 | CPN1 (0.43) | KMT2ACPN1CPB2ALDH1A1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |