Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.46 |
| ▸ | CPN1 | P15169 | 1/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | DDX3X | O00571 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3402993 | 1.00 | PTGS1 (0.60) | PTGS1PTGS2KMT2AMT-CO2CPN1 | |
| SCHEMBL1000053 | 0.86 | PTGS1 (0.45) | PTGS1PTGS2KMT2ACPN1CPB2 | |
| SCHEMBL9158035 | 0.84 | KMT2A (0.47) | PTGS1PTGS2KMT2ACPN1CPB2 | |
| SCHEMBL9158042 | 0.84 | KMT2A (0.47) | PTGS1PTGS2KMT2ACPN1CPB2 | |
| SCHEMBL6163227 | 0.83 | SMN1; SMN2 (0.48) | PTGS1PTGS2KMT2ACPN1CPB2 | |
| SCHEMBL5796124 | 0.82 | APP (0.47) | PTGS1PTGS2KMT2ACPN1CPB2 | |
| SCHEMBL27573545 | 0.82 | CPN1 (0.50) | PTGS1PTGS2KMT2ACPN1CPB2 | |
| SCHEMBL29484096 | 0.81 | PTGS1 (0.62) | PTGS1PTGS2KMT2AMT-CO2HPGD | |
| SCHEMBL1653533 | 0.81 | PTGS1 (0.62) | PTGS1PTGS2KMT2AMT-CO2HPGD | |
| SCHEMBL7806911 | 0.81 | PTGS1 (0.62) | PTGS1PTGS2KMT2AMT-CO2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250109139-A1 | TRICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2025-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250109139-A1 | TRICYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | PARK7, HADH, BDNF | PTGS1 1429/4885PTGS2 2669/4885KMT2A 3812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.