Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30662020 | 0.80 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL14288834 | 0.77 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL9157389 | 0.75 | KDM4E (0.51) | ALDH1A1KDM4ESMN1; SMN2MAPK1GRM2 | |
| SCHEMBL30662029 | 0.74 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL30662024 | 0.74 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL30662023 | 0.74 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL30662018 | 0.74 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL11462985 | 0.73 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL11275890 | 0.73 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPK1 | |
| SCHEMBL30662022 | 0.73 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34918-E | Antihistamines, muscle relaxants | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| US-5013736-A | 5-lipoxygenase inhibitors, smooth muscle relaxants | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-05-07 | — | — | US | disclosed |
| EP-0376223-A2 | Azaazulene derivative, process for preparing the same, and antiallergic agent and antiinflammatory agent containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1990-07-04 | — | — | EP | disclosed |