Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.62 |
| ▸ | NPC1 | O15118 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | STAT3 | P40763 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 2/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10558448 | 1.00 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9153709 | 1.00 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9153631 | 1.00 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9159558 | 1.00 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9154929 | 1.00 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9161241 | 1.00 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9158288 | 1.00 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9159826 | 1.00 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9161236 | 1.00 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 | |
| SCHEMBL9160231 | 1.00 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1MAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473208-B1 | Liquid crystal compounds containing a pyrazine or pyridine ring | MERCK PATENT GMBH (DE) | 1995-03-15 | — | — | EP | disclosed |
| EP-0473208-A2 | Liquid crystal compounds containing a pyrazine or pyridine ring | MERCK PATENT GmbH (DE) | 1992-03-04 | — | — | EP | disclosed |
| US-4913837-A | Heterocyclic compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-03 | — | — | US | disclosed |
| US-4879060-A | 2-phenylpyridine derivatives and liquid crystal compositions including same | SEIKO EPSON KABUSHIKI KAISHA (JP) | 1989-11-07 | — | — | US | disclosed |
| US-4684220-A | 2-phenylpyridine derivatives and liquid crystal compositions including same | SEIKO EPSON KABUSHIKI KAISHA (JP) | 1987-08-04 | — | — | US | disclosed |