SCHEMBL9158385

SCHEMBL9158385

COC(=O)C1OC(OC)C=CC1C

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
ITGA4 P13612 1/20 0.33
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
POLB P06746 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
PPM1B O75688 1/20 0.30
PTPN1 P18031 1/20 0.30
PPP1CC P36873 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7199816 0.68
SCHEMBL34475892 0.68
SCHEMBL7199814 0.68
SCHEMBL7199822 0.68
SCHEMBL15325114 0.68
SCHEMBL10600065 0.67 PPM1B (0.41) ALDH1A1MAPTITGA4CA12CA1
SCHEMBL8601101 0.67 PPM1B (0.41) ALDH1A1MAPTITGA4CA12CA1
SCHEMBL9541118 0.67 PPM1B (0.41) ALDH1A1MAPTITGA4CA12CA1
SCHEMBL9163331 0.67 ALDH1A1 (0.33) ALDH1A1MAPTITGA4
SCHEMBL7150348 0.67 SUCNR1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0494771-B1 Process for producing optically active dihydropyran derivatives TAKASAGO PERFUMERY CO LTD (JP) 1995-04-05 EP disclosed
US-5155240-A Process for producing optically active dihydropyran derivative TAKASAGO INTERNATIONAL CORPORATION (JP) 1992-10-13 US disclosed
EP-0494771-A1 Process for producing optically active dihydropyran derivatives Takasago International Corporation (JP) 1992-07-15 EP disclosed