Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.38 |
| ▸ | ACACB | O00763 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766643 | 0.96 | FFAR1 (0.36) | FFAR1ACACBTSHRHSD17B10NISCH | |
| SCHEMBL9158273 | 0.96 | FFAR1 (0.40) | FFAR1ACACBCHRM2S1PR1FPR1 | |
| SCHEMBL9155712 | 0.92 | TSHR (0.43) | FFAR1TSHRHSD17B10NISCHS1PR1 | |
| SCHEMBL9156038 | 0.91 | HSD17B10 (0.49) | FFAR1TSHRHSD17B10CHRM2MAPT | |
| SCHEMBL9766638 | 0.90 | HSD17B10 (0.48) | FFAR1TSHRHSD17B10NPC1MAPT | |
| SCHEMBL9160634 | 0.89 | CYP2A6 (0.36) | FFAR1ACACBFFAR4NPC1MAPT | |
| SCHEMBL9153691 | 0.87 | FFAR1 (0.39) | FFAR1TSHRHSD17B10FFAR4NPC1 | |
| SCHEMBL9158620 | 0.86 | HSD17B10 (0.42) | FFAR1TSHRHSD17B10CHRM2FFAR4 | |
| SCHEMBL9157598 | 0.85 | HSD17B10 (0.44) | FFAR1TSHRHSD17B10CHRM2FFAR4 | |
| SCHEMBL9874595 | 0.84 | HSD17B10 (0.39) | FFAR1TSHRHSD17B10MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-B1 | PYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 1995-03-08 | — | — | EP | disclosed |
| US-5205962-A | Stable liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-27 | — | — | US | disclosed |
| WO-1991004248-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |