Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.36 |
| ▸ | ACACB | O00763 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | FPR1 | P21462 | 1/20 | 0.30 |
| ▸ | FPR3 | P25089 | 1/20 | 0.30 |
| ▸ | GPR183 | P32249 | 1/20 | 0.30 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158563 | 0.96 | FFAR1 (0.38) | FFAR1ACACBTSHRHSD17B10NISCH | |
| SCHEMBL9160634 | 0.93 | CYP2A6 (0.36) | FFAR1ACACBCYP2A6FFAR4 | |
| SCHEMBL9158273 | 0.92 | FFAR1 (0.40) | FFAR1ACACBCHRM2S1PR1FPR1 | |
| SCHEMBL9154284 | 0.89 | CYP2A6 (0.39) | FFAR1ACACBCYP2A6FFAR4 | |
| SCHEMBL9155712 | 0.88 | TSHR (0.43) | FFAR1TSHRHSD17B10NISCHS1PR1 | |
| SCHEMBL9766633 | 0.88 | HSD17B10 (0.39) | FFAR1TSHRHSD17B10CHRM2FFAR4 | |
| SCHEMBL9874595 | 0.87 | HSD17B10 (0.39) | FFAR1TSHRHSD17B10 | |
| SCHEMBL9156038 | 0.87 | HSD17B10 (0.49) | FFAR1TSHRHSD17B10CHRM2 | |
| SCHEMBL9766638 | 0.86 | HSD17B10 (0.48) | FFAR1TSHRHSD17B10 | |
| SCHEMBL9153691 | 0.84 | FFAR1 (0.39) | FFAR1TSHRHSD17B10FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-A1 | PYRIDINE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |